I asked a similar question a while back.
My answers then still apply.
1. Antoine Cason, CB, Arizona, 6'0", 185...in this case it is not a homer pick because I live here. I think this guy is the best CB prospect in the draft, the best ever from UA (yep, even over Chris McAllister), and a perfect bookend for Terence Newman. He's blazing fast, recovers really quick, and is a ball hawk. Pac 10 teams simply will not challenge him.
2. Calais Campbell, DE, Miami, 6'8", 282...wait until you get a look at this kid. Reminds me a bit of Too Tall, but isn't as thick. Is faster than Too Tall. Has a great swim move and a good rip. If Chris Canty, Jason Hatcher, and Marcus Spears don't make big leaps forward this year he may be #1 instead of #2.
3. Jake Long, OT, Michigan, 6'7", 313...before he committed to go back to Michigan, I was kind of hoping he'd be our pick. I really like Doug Free and James Marten and can see them as potential bookend OTs for years. This guy is a no doubt about it to me. I couldn't turn that down. OL is never sexy, but it is vital to winning. This guy will take his job seriously and personal.