There's no way to stop a quarterback like Drew Brees. You hope either he has a bad day or the players around him have a bad day.
However, we're in luck because we can say the same thing about Tony Romo.
"Many of the greatest things man has achieved are not the result of consciously directed thought, and still less the product of a deliberately coordinated effort of many individuals, but of a process in which the individual plays a part which he can never fully understand." - Friedrich Hayek