Don't know about Reagor, but I think Ruggs is going to be gone pretty early. Guys with 4.3 burner speed are scoring a crazy amount this season since defenders are no longer allowed to cover them. Just look at the rookies this year - DK Metcalf, Hollywood Brown, Mecole Hardman - speed translates easily to today's NFL.
Ruggs is a legit 4.2 guy, and I don't say that lightly. You may only see one guy that fast once every draft class. On top of that, Ruggs is actually good at playing football too. The ubiquitous comp you're going to see for him is Tyreek Hill, and barring injury, I bet he goes in the top half the first round.