Penn will be defending the Lightweight title against Florian on that same card.
Unfortunately for Griffin I think he's going to struggle no matter where it goes. Anderson is outstanding on his feet and he's pretty darn great, and dangerous, on the ground and on his back.
I think Griffin is going to be in for a long night of being beat up but what I'm hoping he does is take the beating and keeps coming, like he's known to do at times, and shows that heart and fire. Then even when he loses (and yes I think he's going to definately lose) he'll still look good in the eyes of his fans and such cause he showed that warrior toughness.