Tri Channel, and stability.
Mostly coming from a professional audio viewpoint. Audio is one of the areas where you can really push the limits on your computer set up. Earlier this year there were all sorts of problems with various 1155motherboards performing quite erratically with large audio setups. These sorts of things are not as extensively tested in advance.
Leading edge setups can get you leading edge problems.
Again, if you aren't already in the field, you probably don't have to consider that decision.