Yes, we can. This is not to say we will but we certainly can. Denver is not a great defensive team. They don't defend the Pass all that well statistically and they only run the ball about middle of the road. This might be because they pass the ball so well but if you can force them into having to run in Red Down situations or 3rd downs, they will struggle with that. Moreno does have a history of fumbling and Manning is due for a few INTs. We have the personnel to score with them, so long as we play a well called game and don't become one dimensional. I am not convinced that their OL can stop our pass rushers so if we can get pressure, that changes the game significantly. Shortens up the pass routes and then it becomes a matter of tackling well in the open field. No YAC. Turnovers are the ultimate statistic in the NFL. If we take care of the ball and do the things we need to, in order to score TDs as opposed to FGs, if we play good defense, yes, we can win.
Now, as I said earlier, CAN win and WILL win are two different things.