I had heard about it but never really looked into until a little while back just to see what the attraction was.
Looks like you just turn processing power into money. The problem seems to be that the processing power required is ridiculous. Some people have found ways to get the most bang for their buck from certain rigs but a lot of the hardware parts are expensive as all hell.
On top of that, as time goes by the computing power needed to generate one "bit" or whatever they call it is also rising. So while you might be able to get a setup that might be able to generate a few hundred bucks per month, that same system will start falling behind and you'll be generating less and less.
Additionally, people have basically turned smaller areas into farms. They'll rig up a couple dozen of these small machines and make good money on it. Problem here is that small users who may want to have 1 machine or whatever are working with limited resources and the life cycle of their product is diminished as these power users are cranking out processing power at an ever increasing rate.
Lastly, the price of electricity to run some of this stuff is pretty high. Imagine your computer running full bore nonstop.
It's an interesting idea. You should check YouTube for some of the setups people are running. At this stage in the game though I don't think it would be worth trying without a specialized machine and there's no guarantee that it won't be too slow to do anything with shortly down the line.