WRT Osa being a good 3-4 DE, the DEs you want in the classic 3-4 are not just big, they're also very tall or long. Think of Spears. You want your 3-4 DE to line head-up on the tackles and keep the tackle out of their chest, so they can defend 2 gaps. You don't want a DE who gets engulfed.
Osa is short, but he's got really long arms, so I wouldn't categorically write him off. But he gets engulfed right now as a one-gap player, and you'd be putting him in more of those bad situations as a two-gap player. He could probably make it work, cause good football players are good football players, but it's not his best fit.
The holy grail of the old school 3-4 was the "pressure five" - the DE who could cover two gaps in run defense and also get to the the QB on passing plays. Those dudes were unicorns. They were never big sack guys, because they had to run straight through a tackle on their pass rush, but they could give the defense pressure without blitzing and they freed up the rush LBs even further. Most of your good 3-4 defenses had one - off my head, I'm thinking of players like Justin Smith with the Niners, Aaron Smith with the Steelers, Richard Seymour, or Haloti Ngata.