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Scientists say they have found a way to disarm the AIDS virus in research that could lead to a vaccine. Researchers have discovered that if they eliminate a cholesterol membrane surrounding the virus, HIV cannot disrupt communication among disease-fighting cells and the immune system returns to normal.
Scientists have discovered that HIV needs cholesterol, which it picks up from the first immune cells it infects, to keep the virus' outer membrane fluid. That allows it to communicate with - and disrupt - the body's immune system.
The long-term effect of this disrupted communication is to destroy the body’s normal defense against the AIDS virus, which is responsible for 1.8 million deaths each year.
But researchers say they can prevent HIV from damaging the immune system, if they remove the cholesterol from the virus’ outer membrane.
David Graham is a molecular biologist at The Johns Hopkins University in Baltimore, Maryland.
“By stealing cholesterol from the envelope of the virus, we can neutralize the subversion," said Graham. "We’ve broken the code; we can shut down the type of interference that HIV is having on the immune system.”
Complete Story
Scientists have discovered that HIV needs cholesterol, which it picks up from the first immune cells it infects, to keep the virus' outer membrane fluid. That allows it to communicate with - and disrupt - the body's immune system.
The long-term effect of this disrupted communication is to destroy the body’s normal defense against the AIDS virus, which is responsible for 1.8 million deaths each year.
But researchers say they can prevent HIV from damaging the immune system, if they remove the cholesterol from the virus’ outer membrane.
David Graham is a molecular biologist at The Johns Hopkins University in Baltimore, Maryland.
“By stealing cholesterol from the envelope of the virus, we can neutralize the subversion," said Graham. "We’ve broken the code; we can shut down the type of interference that HIV is having on the immune system.”
Complete Story