Cancer Drug Kills Every Kind of Tumor: Study

[jobberone]

Stanford University scientists have discovered a single drug that has killed or shrunk every kind of cancer tumor it has been used against — a new anti-cancer weapon that some have described as a kind of medical Holy Grail.

The drug blocks a protein produced in large amounts by cancer cells — called CD47 — that keeps the body’s immune system from fighting tumors. By shutting down the CD47 production, the new antibody drug effectively leaves cancer cells vulnerable to the body’s own natural defense mechanisms.
Tests of the drug found that it destroyed several kinds of human cancer cells transplanted into mice — including breast, ovary, colon, bladder, brain, liver, and prostate tumors — by prompting the rodents’ immune systems to kill the cancer cells.

“We showed that even after the tumor had taken hold, the antibody can either cure the tumor or slow its growth and prevent metastasis,” said biologist Irving Weissman of the Stanford University School of Medicine, in an interview with Science Magazine.

http://www.newsmaxhealth.com/Health.../496736?s=al&promo_code=12F7B-1#ixzz2OxCyoBjr

 

[DFWJC]

That's really promising.
Thanks for posting.

 

[visionary]

Stanford University scientists have discovered a single drug that has killed or shrunk every kind of cancer tumor it has been used against — a new anti-cancer weapon that some have described as a kind of medical Holy Grail.

The drug blocks a protein produced in large amounts by cancer cells — called CD47 — that keeps the body’s immune system from fighting tumors. By shutting down the CD47 production, the new antibody drug effectively leaves cancer cells vulnerable to the body’s own natural defense mechanisms.
Tests of the drug found that it destroyed several kinds of human cancer cells transplanted into mice — including breast, ovary, colon, bladder, brain, liver, and prostate tumors — by prompting the rodents’ immune systems to kill the cancer cells.

“We showed that even after the tumor had taken hold, the antibody can either cure the tumor or slow its growth and prevent metastasis,” said biologist Irving Weissman of the Stanford University School of Medicine, in an interview with Science Magazine.

http://www.newsmaxhealth.com/Health.../496736?s=al&promo_code=12F7B-1#ixzz2OxCyoBjr

its called a BULLET

it kills all kinds of tumors by killing the host

 

[burmafrd]

Believe it when it really comes out. There have been rumors before of a magic bullett drug.

 

[notherbob]

Sounds great but even if it really works, somehow I doubt the public will ever have it available as a treatment, at least in this country.

 

[Yeagermeister]

Sounds like the beginning of all the zombie movies

 

[LynnFoster]

I've seen Weissman give talks before, he is a spectacularly bright guy. He is one of the top stem cell guys around, interesting that he is doing this type of work too.

 

[jobberone]

Sounds like the beginning of all the zombie movies

:laugh2: It does. I Am Legend. <ghost sounds>

To others, this is not a toxic drug but only blocks production of a substance that cancers produce which causes the body NOT to attack the cancer. The drug allows the body to fight the cancer naturally with the immune system.

 

[jobberone]

I've seen Weissman give talks before, he is a spectacularly bright guy. He is one of the top stem cell guys around, interesting that he is doing this type of work too.

Interesting. Can you give us any more info? And you should post more!

 

[LynnFoster]

Interesting. Can you give us any more info? And you should post more!

Thanks! Weissman is one of the big fish at Stanford and in Stem Cells/Regenerative Medicine in general. I don't know him but he seems like a class act. If you have tracked that space there has been a lot of hype, but Weissman and a few others have said long and loud that it was going to take a long time and that adult stem cells were what people should focus on rather than embryonic stem cells (which got 95% of the press). He founded a company with David Anderson of Caltech called Stem Cells Inc.

Him and guys like Robert Chow were totally on the mark in what they said, if you look at the real breakthroughs it has been from taking your own stem cells from your body to reuse them. All the hype and loud shouting was around embryonic stem cells and almost nothing has come out of that area.

 

[jobberone]

Thanks! Weissman is one of the big fish at Stanford and in Stem Cells/Regenerative Medicine in general. I don't know him but he seems like a class act. If you have tracked that space there has been a lot of hype, but Weissman and a few others have said long and loud that it was going to take a long time and that adult stem cells were what people should focus on rather than embryonic stem cells (which got 95% of the press). He founded a company with David Anderson of Caltech called Stem Cells Inc.

Him and guys like Robert Chow were totally on the mark in what they said, if you look at the real breakthroughs it has been from taking your own stem cells from your body to reuse them. All the hype and loud shouting was around embryonic stem cells and almost nothing has come out of that area.

Good stuff. I'll ask around about him and see if I can come up with anything. I'm afraid I don't know much at all about this. They hadn't invented stem cells when I was taught. Well very basic stuff about pluripotent cells. I have some friends in regenerative genetics and I'll talk with them tomorrow.

 

[notherbob]

:laugh2: It does. I Am Legend. <ghost sounds>

To others, this is not a toxic drug but only blocks production of a substance that cancers produce which causes the body NOT to attack the cancer. The drug allows the body to fight the cancer naturally with the immune system.

It does, indeed, sound like a good thing and I hope it is something that can be brought to bear against cancers. I expect; however, there to develop some reason why it cannot be implemented - there always is whenever some breakthrough is announced. We seem to always have to stay with the present modalities for some reason.

 

[jobberone]

It does, indeed, sound like a good thing and I hope it is something that can be brought to bear against cancers. I expect; however, there to develop some reason why it cannot be implemented - there always is whenever some breakthrough is announced. We seem to always have to stay with the present modalities for some reason.

Oh, shah. Don't be so negative Bob. This is huge news. Unless we find some unforeseen side effect this sounds extremely promising. And we are getting more and more genetically targeted drugs that use our own cells to deliver cytotoxic drugs to just cancer cells and not the healthy cells.

We're getting closer.

 

[StarMan2112]

It does, indeed, sound like a good thing and I hope it is something that can be brought to bear against cancers. I expect; however, there to develop some reason why it cannot be implemented - there always is whenever some breakthrough is announced. We seem to always have to stay with the present modalities for some reason.

Greed is king. Too much money to be made off cancer patients.

 

[ScipioCowboy]

Sounds great but even if it really works, somehow I doubt the public will ever have it available as a treatment, at least in this country.

In which country would It be made Available?

Most new medicines and cures are developed here.

 

[Hoofbite]

It does, indeed, sound like a good thing and I hope it is something that can be brought to bear against cancers. I expect; however, there to develop some reason why it cannot be implemented - there always is whenever some breakthrough is announced. We seem to always have to stay with the present modalities for some reason.

Usually it's safety. Antibodies are tricky because they can stimulate an immune response that is more deadly than what they are trying to treat.

 

[Hoofbite]

Greed is king. Too much money to be made off cancer patients.

As opposed to treating short-term and letting people die, couldn't they make more if they had a drug that would keep people alive as long as they took it?

 

[TheSport78]

Sounds great but even if it really works, somehow I doubt the public will ever have it available as a treatment, at least in this country.

This. The pharma companies would lose billions of dollars.

Sad world we live in.

 

[jobberone]

It take billions to develop a drug when you're having to look at hundreds of chemicals to find one promising one. Then you have to make sure its safe which cost billions more. So yes some are expensive because companies have to make a profit so they can actually find and make drugs.

Not so long ago we didn't cure cancers at all then just a few. Now we are on the precipice of actually curing and not just treating most cancers.

 

[Denim Chicken]

Just like every other seemingly 'breakthrough', you will never hear about this again.