Chicago played it extremely well last season with Urlacher playing the deep middle. Double safety high with the MLB running to the deep middle was seen against us many times last season.
The "Tampa 2" is just one of many looks we will see. I have heard of cover 1, cover 2, cover 3, man under, single safety, press, press bail, various LB, S, and CB blitz all being ran during TC. The main difference is that there are not going to be 5 checks at the line for every player.