I think you're safe. You're not giving up 268 yards.
But if you're talking not seeing an Eagle in general have the rushing record, then lose the game but keep him in check. If Philly wins and Barkley has 100-120 yards, he's limited to likely sitting out next week. Even with a Philly win, If he's sniffing the record, and with Sirianni being the child he is, Saquon gets pounded next week instead of resting in prep. for a tough home playoff opener. If the Cowboys win, all bets are off for next week cuz the division will still be in the balance.