Quarterbacks with pocked presence know when the throw the ball or run. Dak doesn't have that. He had ample time to find a receiver and if none were open, throw it away or run. He did neither.
But let's say you're right, the last chance to pull this game out was the 4th down throw to a wide open Zeke, and he missed it badly, with NO PRESSURE. Bills were backed up to prevent an end zone td throw.
This loss was at least 50% on Dak, that wasn't the only off throw, and there were several other passes that Cobb, Cooper and others had to make a huge effort to catch. Watch Brady's or Brees' or Rodgers throws, most of them are dead on target. Dak makes some great throws, but far too few compared to misses or passes that require tremendous effort to catch.
I will give Dak a bit of slack, he came to this team with a running game that was second to none in the league, he's not used to being a few years ago Brees, or a P. Manning, etc. Those guys are used to being in a high volume passing offense.
I said at the beginning of the year, I would give Dak the entire season to improve. For a while it appeared he was doing so, but lately he has regressed. He's got 5 games left, I'll revisit his performance after the season, but it ain't looking good. I'll support him until then, and would like everybody to get behind him, just because he's doing the best he can with a greenhorn OC and a doofus head coach, and if a new coach is hired after the season, I'd still like to see him stick around, if for no other reason than he deserves it based on who his coaches have been, Wade Wilson ******** his development, he's durable so good coaching may turn him around, but we won't know that until next year....