I think I'd rest the guys with soft tissue injuries, and play the guys who are hurt (like Murray and, probably, Romo) but who are otherwise able to play without risk of aggravating an existing problem. It's another chance to practice your blitz pickups and you can always throw the ball away or take a sack. If the Cowboys get up by a few scores, you can pull the starters. There's something to be said for keeping the routine and the mindset that the focus is on each individual plays and that you don't look ahead. You just try to do your best every time you step on the field.
It sure sounded to me today like Garrett was saying in his presser that he was going to play his healthy starters.