Billyd
Well-Known Member
- Messages
- 2,235
- Reaction score
- 1,036
Thank you for clearing up some of those issues. I DONT think I was ever vaccinated for chicken pox. I made a post a few minutes ago in regards to that..l presumed I was before i went to thailand but that was before the public apparently was vaccinated against it..This was in the late sixties, but do to the area in asia, I was vaccinated against things some might not have been..You don't get exposed to live varicella virus by vaccination; it's a purified protein derivative that fools the immune system into making antibodies without any disease exposure.
Almost all modern vaccines are of this type. We might expect therefore, that if everyone gets vaccinated against varicella, we will see a steady decline in the number of Herpes Zoster (shingles) cases over time. This can be very debilitating and difficult to treat, especially in the elderly. The new Shingrix vaccine is about 95% effective.
If you get a vaccination and don't get immunity, then either the vaccine did not stimulate an adequate immune response (not enough antibodies), or the strain of virus you contracted was not covered by the vaccine you received.
That last point addresses the dilemma with influenza immunity.
Pathogenic influenza strains change every year, specifically the protein sources that are traditionally available to stimulate antibody production.
Whatever is present in southeast Asia early in the year, those are the strains that are chosen to likely appear in our hemisphere later in the year. To maximise our potential for coverage, multistrain vaccines have emerged in recent years with up to 4 strains of Influenza A&B. But still we can miss covering the predominant strain in a given area; common international travel has made this even more problematic.
Research has made some strides in the last 2 years in the development of a novel source of influenza viral protein which does not mutate or change yearly. It has shown excellent immune response in mice without the need for an adjuvant (a substance added to increase antibody production). This is likely to cover most influenza strains, and may only require a booster every 10-20 years. This technology may still be more than 5 yrs away from availability; human trials have yet to start. Such a vaccine could save thousands of lives worldwide each year, not to mention all the serious and costly illness.
I've been involved in vaccine research (as well as other medical clinical trials) for over 20 years. There is nothing dangerous about a vaccination, no reason to fear negative outcomes.
The only likely side effect is a local reaction of mild redness and/or discomfort, and possibly a bit of mild fever and/or malaise. This is simple a "foreign substance" reaction, eliciting a mild inflammatory response, which results in the desired antibody production. I repeat, you cannot get the disease from a non-live virus.
Ever since Edward Jenner performed the first vaccination in 1796, research in this method of disease prevention has been ongoing.
Still, over 500,000 people die of influenza each year, approximately 20-40 thousand of those in the US. While it's true that the very young and the very old are the most vulnerable to serious consequences, any previously vigorous and healthy adult can die of this disease. As an example, there was a 32 yr old healthy male in my community who died last winter.
If you love your family, keep them and yourself up to date on vaccinations.
Some points that i am middle of the fence on are the multiple virus vaccinations, and if course the flu vaccine. i mentioned earlier i am pro vaccine i have a healthy daughter 20 to prove it, and she received the required vaccines as suggested..
I think a lack of research into the facts more prevalent than anything, i dont subcribe to the vaccinations causing autism..
However the flu vaccine and the recent inefectiveness has caused me to be concerned there. Mutation DRIVING the bus leading to a worse or more virulent strain of the flu, is a concern. Although im sure public health a focus of many, we from time to time do make mistakes. THEY do get out in the open..
Always good to have new knowledge of what is happening now. Thank you!
Last edited: