Have you seen any speculation that the series is about the end of the world and Rick will be the only one left in the world who is not a zombie by series end?
No... Haven't come across that.
That could happen but I doubt it. As we've seen so far in the series, there are other living people out there. They may not be friendly... they may have selfish goals but they are out there. And sooner or later groups that are friendly and aren't looking to rape & ransack are going to combine and keep combining... And they'll have kids and the population will slowly grow. The big question will be is there a "cure" to keep someone from turning once they have died? If they do come up with something that would greatly help. At this juncture we don't know if anyone is immune. The guy at the CDC didn't think so, but that doesn't mean it that immunity doesn't exist.
The thing to keep in mind if this was really happening, i.e. a zombie outbreak, that these reanimated corpses would only be mobile for a relatively short-time... Just a few years until the ravages of weather, temperature and wild critters would simply make them immobile. Those decaying body parts are going to wear out.
Also keep in mind that folks in the colder regions are probably having a much easier time dealing with this because the undead are becoming frozen for some period of time. I mentioned in another post that it wouldn't be a surprise to learn that a great many people simply moved north to avoid much of what was going on. I mean some smart folks would have to think, "Frozen bodies can't move." And if they can't move they can't feed on you and create more undead and they're easy pickings to be made immobile permanently.